Wednesday, September 24, 2008

Kalanchoe pinnata


Botanical name : Kalanchoe pinnata (Lam.) Pres.

Family : Crassulaceae

SANSKRIT SYNONYMS :Astibhaksha, Parnabeeja

AYURVEDIC PROPERTIES

Rasa : Tikta, MadhuraGuna : Sara, Lakhu Virya : SeetaVipaka : Katu

PLANT NAME IN DIFFERENT LANGUAGES

Hindi : Jakh me hayat Malayalam : Ilayinmeltai, Ilamulachi.

Common names: Air plant, balangban, bruja, clapper bush, coirama, coirama-branca, coirama-brava, curtain plant, dipartenga, farine chaude, fel pavo, floppers, folha-da-costa, green love, hoja de aire, life leaf, live forever, mexican loveplant, miracle leaf, motta patti, paichecara, pashipadeh, paochecara, pirarucu, potagoja, sayao, saiĆ£o, siempre viva

Distribution – Cultivated as a garden plant; also growing wild.

PLANT DESCRIPTION : An erect perennial succulent herb grows up to 1 meter in height. Leaves opposite, decussate, long petioled, acute, dentate or crenate with vegetative buds. Flowers reddish, found in large panicles. Fruits membranous, enclosed by persistent calyx and corolla. Seeds elliptic and smooth.

MEDICINAL PROPERTIES : Plant pacifies vitiated pitta, vata, hemorrhoids, menorrhagia, wound, cuts, boils, ulcers diarrhea, vomiting, blood vomiting and inflammations.

Main actions :
kills bacteria, kills viruses, kills fungi, reduces fever, heals wounds, suppresses coughs, relieves pain, reduces inflammation, prvents ulcer, increases urination ,lowers cholesterol, constricts blood vessels, mildly sedative, blocks histamine,relaxes muscles.

Useful part : Leaves.

Chemical contituents :Kalanchoe is rich in alkaloids, triterpenes, glycosides, flavonoids, steroids and lipids. The leaves contain a group of chemicals called bufadienolides which are very active and have sparked the interest of scientists. They are very similar in structure and activity as two other cardiac glycosides, digoxin and digitoxin (drugs used for the clinical treatment of congestive heart failure and related conditions). Kalanchoe's bufadienolides have demonstrated in clinical research to possess antibacterial, antitumorous, cancer preventative, and insecticidal actions.
The main plant chemicals found in kalanchoe include: arachidic acid, astragalin, behenic acid, beta amyrin, benzenoids, beta-sitosterol, bryophollenone, bryophollone, bryophyllin, bryophyllin A-C, bryophyllol, bryophynol, bryotoxin C, bufadienolides, caffeic acid, campesterol, cardenolides, cinnamic acid, clerosterol, clionasterol, codisterol, coumaric acid, epigallocatechin, ferulic acid, flavonoids, friedelin, glutinol, hentriacontane, isofucosterol, kaempferol, oxalic acid, oxaloacetate, palmitic acid, patuletin, peposterol, phosphoenolpyruvate, protocatechuic acid, pseudotaraxasterol, pyruvate, quercetin, steroids, stigmasterol, succinic acid, syringic acid, taraxerol, and triacontane.

BIOLOGICAL ACTIVITIES AND CLINICAL RESEARCH :
Many of kalanchoe's traditional uses can be explained by the clinical research conducted thus far on the plant. The traditional use for infectious conditions (both internally and externally) is supported by research indicating kalanchoe leaves have antibacterial, antiviral and antifungal activity. The leaf and leaf juice have demonstrated significant in vitro antibacterial activity towards Staphylococcus, E. coli, Shigella, Bacillus and Pseudomonas, including several strains of multi-drug resistant bacteria. A water extract of kalanchoe leaves (administered topically and internally) has been shown to prevent and treat leishmaniasis (a common parasitic disease in tropical countries which is transmitted by the bite of sand flies) in both humans and animals. In addition to its antibacterial properties, kalanchoe's traditional uses for upper respiratory conditions and coughs might be explained by research demonstrating that the leaf juice has potent anti-histamine and anti-allergic activity. In an in vivo study (with rats and guinea pigs) the leaf juice was able to protect against chemically induced anaphylactic reactions and death by selectively blocking histamine receptors in the lungs.
In another in vivo study scientists validated kalanchoe's use for gastric ulcers; a leaf extract protected mice from such ulcer-inducers as stress, aspirin, ethanol and histamine. Other in vivo research confirms that kalanchoe can reduce fevers, and provides anti-inflammatory, pain-relieving and muscle relaxant effects. It's anti-inflammatory effects have been partially attributed to the immunomodulatory and immune suppressant effect documented by scientists in several studies. In several in vivo and in vitro studies, researchers reported that extracts of the leaf and/or juice suppressed various immune reactions, including those which trigger an inflammatory response as well as a histamine response. Kalanchoe has also shown sedative and central nervous system depressant actions in animal studies. These effects were attributed partially to the leaf extract demonstrating the ability to increase the levels of a neurotransmitter in the brain called GABA (gamma aminobutyric acid).

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